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These 10 habits can make your immune system shut down, so follow this advice and your body will thank you.

1. Junk the Junk Food

Combined with sedentary lives, a poor diet is estimated to kill between 310,000 and 580,000 Americans each year.

So, how bad is junk food for your immune system?

Experts have known for some time that when a person is malnourished, her immune system is weakened. When you restore the person to normal nutrition, her immune system improves, which is no surprise. But what they're just learning is that when you continue to improve nutrition beyond mere adequacy, the immune system continues to improve, even in healthy people.

One thing that a lot of junk food has in common is excess fat. Fats, especially polyunsaturated fats, tend to suppress the immune system. Cut your total fat intake to no more than 25% of daily calories.

Another bad component of junk food is excess sugar. Sugar inhibits phagocytosis, the process by which viruses and bacteria are engulfed and then literally chewed up by white blood cells.

2. Dodge Those PCBs

It takes just one exposure of less than one-millionth of a gram for immunotoxic contaminants such as polychlorinated biphenyls (PCBs), mercury, certain pesticides, and dioxin-like substances to disrupt the immune function of innocent wildlife. Since these chemicals can stay in the environment for decades, vulnerable wildlife species have no escape from their devastation. Moreover, not only do these toxins become more concentrated as they move their way up the food chain, they can also cause life-threatening autoimmune reactions--the immune system's inability to tell the difference between the body's own tissues and foreign invaders.

So what can you do? Reduce your exposure as much as possible to unnecessary toxins. Stay away from cigarette smoke, excess alcohol, and illicit drugs. Buy organic produce when possible. Rinse your fruits and vegetables thoroughly to remove pesticides. Switch to natural gardening methods and stay indoors or go away when your neighbors are using pesticides. Choose cleansers, paper goods, and other products that are made with less toxic materials. Read food labels vigilantly and avoid products that contain unnecessary chemicals.

3. Avoid Sleep Deprivation

Sleep deprivation has a powerfully detrimental effect on your immune system. The perfect example is college students who get sick after pulling all-nighters cramming for exams.

If you're tired when you wake up in the morning, you're not getting enough sleep, or maybe not enough quality sleep. Either way, your immunity is probably compromised. Poor sleep is associated with lower immune system function and reduced numbers of killer cells that fight germs. Killer cells are also the part of the immune system that combats cells that divide too rapidly, as they do in cancer. Lower their numbers and you may be at greater risk for illness.

Studies have shown that chronic sleep deprivation also contributes to heart disease, gastrointestinal problems, and other medical illnesses. One study on the effects of sleep deprivation showed that a group of men restricted to 4 to 6 hours of sleep per night experienced changes in hormone function and carbohydrate metabolism that mimic aging changes; the lack of sleep was making them older faster.

4. Release Yourself from the Stress Trap

No doubt about it, stress is an Immune Buster.

The loss of a job, the death of a spouse, the breakup of a marriage--these are all examples of situations that can trigger a vigorous stress response in the body. There is compelling scientific evidence that chronic stress causes a measurable decline in the immune system's ability to fight disease. Severe and chronic stress have a direct impact on the immune system that can cause disease or change the course of a preexisting disease. For example, studies have indicated that higher levels of stress hormones lead to more rapid cancer progression.

Periods of extreme stress can result in lower natural killer cell count, sluggish "killer T" cells, and diminished macrophage activity that can amplify the immune response. In fact, widows and widowers are much more likely to get sick during the first year following the death of their spouse than their peers who have not experienced a major loss.

5. Adopt an Optimistic Outlook

Even subtle shades of sadness can weaken your immune system. Here's why:

Studies show that pessimists who look at a half-glass of water and think that it's half-empty don't live as long as optimists, who see the same glass as half-full. When pessimists put a more positive spin on the calamities in their lives, they have less stress and better health. One reason for this could be that optimists take better care of themselves. It could also be due to less stress-related damage to your immune system, such as killer cells that suddenly become pacifists. In one study, cancer patients who completed a special course designed to make them more optimistic had stronger immune systems than those who maintained their woesome ways.

Other research supports the idea that having a negative outlook when under stress can make you and your immune system miss out. A 1998 study at UCLA found that law students who began their first semester optimistic about the experience had more helper T cells midsemester, which can amplify the immune response, and more powerful natural killer cells. The reason? They experienced events such as their grueling first year as less stressful than did their more pessimistic classmates. Researchers say that this establishes the possibility that a person's outlook and mood when stressed might affect responses to common immune challenges such as exposure to cold viruses.

6. Avoid Sedentary Lifestyles

One in four American women doesn't exercise at all, making sedentary lifestyles even more common in women than in men. Sedentary ways have a tremendous impact on health. The benefits of exercise are so great that choosing not to exercise is like throwing away a winning lottery ticket. Millions of Americans suffer from illnesses that can be prevented or treated through exercise, including 50 million people with high blood pressure, 13.5 million with coronary heart disease, and 8 million with type 2 diabetes.

Over time, you should work up to the standard recommendation of five times a week for at least 30 minutes. Experts say that it takes a half-hour of aerobic exercise to sweep white blood cells, key immune system components that are stuck on the blood vessel walls, back into circulation.

Moderate exercise is the key. If your exercise is too intense, it can actually suppress your immune system, which is why marathon runners often get colds after a race. What defines overexertion depends on your fitness level. Consult with your doctor to determine yours before starting an exercise program.

7. Avoid Social Isolation

The cost of social isolation may be higher than we think. Studies show that the fewer human connections we have at home, at work, and in the community, the more likely we are to get sick, flood our brains with anxiety-causing chemicals, and die prematurely.

One study in Sweden showed that those who frequented cultural events such as concerts, museum exhibits, and even ball games tended to live longer than their stay-at-home peers. The key factors could be increased social contact and reduced stress. Other studies have found that people who are isolated may live only half as long as those who have a lot of human contact. Love seems to be an immune system nutrient.

The good news is that these same studies also show that the more human connections we have, the more likely we are to live longer and healthier. Connectedness is the unacknowledged key to emotional and physical health. The more ties you have, the more likely you are to stay well in the first place. Researchers who monitored 276 people between the ages of 18 and 55 found that those who had six or more connections were four times better at fighting off the viruses that cause colds.

8. Stop Smoking

Smoking, and breathing in secondhand smoke, are terrible for your entire body. Cigarette smoke contains more than 4,000 chemical compounds. Of these, at least 43 are known carcinogens.

Secondhand smoke is almost as deadly. Each year, because of exposure to tobacco smoke, an estimated 3,000 nonsmoking Americans die of lung cancer and 300,000 children suffer from lower respiratory tract infections. Secondhand smoke can trigger an asthma attack and aggravate symptoms in people with allergies. In addition, tobacco smoke has been shown to make asthma worse in preschool children and may even cause it.

9. Arm Yourself Against Too Many Antibiotics

The cost of antibiotic resistance is high, both literally and from a health perspective. Literally, while it costs only $12,000 to treat a patient who has tuberculosis that responds to antibiotics, the cost soars to $180,000 for a patient with a multidrug-resistant strain.


10. Use Laughter to Beat Stress

Researchers have found that the positive emotions associated with laughter decrease stress hormones and increase certain immune cells while activating others. In one study conducted at Loma Linda University School of Medicine in California, 10 healthy men who watched a funny video for an hour had significant increases in one particular hormone of the immune system that activates other components of the immune system.

So how can you add a little humor to your life? Simply find reasons to laugh. Rent a funny video; read a book of jokes. Have lunch with a friend known for her sense of humor. Lightening up can really light up your immune system.

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